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Social and scientific priority areas to be tackled by using the supercomputer Fugaku were determined in December 2014 (Priority Issues) and June 2016 (Exploratory Challenges), and research institutions were selected to pursue the goals in these areas. This initiative was completed in March 2020.

1. Priority Issues

Priority Issues
Category Priority issues Organizations
Achievement of a society that provides health and longevity
Innovative drug discovery infrastructure through functional control of biomolecular systems
RIKEN Center for Biosystems Dynamics Research and 6 other institutions
Integrated computational life science to support personalized and preventive medicine
The Institute of Medical Science, the University of Tokyo and 4 other institutions
Disaster prevention and global climate problems
Development of integrated simulation systems for hazards and disasters induced by earthquakes and tsunamis
Earthquake Research Institute, the University of Tokyo and 4 other institutions
Advancement of meteorological and global environmental predictions utilizing observational "Big Data"
Japan Agency for Marine-Earth Science and Technology (JAMSTEC) and other 5 institutions
Energy problems
Development of new fundamental technologies for high-efficiency energy creation, conversion/storage and use
Institute for Molecular Science, National Institute of Natural Sciences and 8 other institutions
Accelerated development of innovative clean energy systems
School of Engineering, the University of Tokyo
and 11 other institutions
Enhancement of industrial competitiveness
Creation of new functional devices and high-performance materials to support next-generation industries (CDMSI)
The Institute for Solid State Physics, the University of Tokyo and 9 other institutions
Development of innovative design and production processes that lead the way for the manufacturing industry in the near future
Institute of Industrial Science, the University of Tokyo and 7 other institutions
Development of basic science
Elucidation of the fundamental laws and evolution of the universe
Center for Computational Sciences, University of Tsukuba and 10 other institutions

2. Exploratory Challenges

Exploratory Challenges
Exploratory Challenge Organizations
Exploratory Challenge 1
Frontiers of Basic Science: Challenging the Limits
Tohoku University and 9 other institutions
Tokyo Woman's Christian University and 3 other institutions
The University of Tokyo
Exploratory Challenge 2
Construction of Models for Interaction Among Multiple Socioeconomic Phenomena
RIKEN Center for Computational Science and other 12 institutions
Tokyo University of Science and other 3 institutions
Exploratory Challenge 3
Elucidation of the Birth of Exoplanets [Second Earth] and the Environmental Variations of Planets in the Solar System
Kobe University and other 8 institutions
Exploratory Challenge 4
Elucidation of How Neural Networks Realize Thinking and Its Application to Artificial Intelligence
Okinawa Institute of Science and Technology Graduate University and other 4 institutions
RCAST, The University of Tokyo